Difference between revisions of "2.1.11 Preregistration"
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== B. Guidance & Expectations == | == B. Guidance & Expectations == | ||
| − | * If study is done to inform a knowledge claim ([[Purpose of research]]), it is strongly recommended to preregister the study protocol before data are collected. | + | * If study is done to inform a knowledge claim ([[2.1.4 Purpose of research]]), it is strongly recommended to preregister the study protocol before data are collected. |
* It is strongly recommended to register systematic review protocols. | * It is strongly recommended to register systematic review protocols. | ||
* Training on planning and benefits of preregistration is highly recommended. | * Training on planning and benefits of preregistration is highly recommended. | ||
| Line 22: | Line 22: | ||
* To consider adding this subject to a training program for new employees or refresher training (if appropriate) | * To consider adding this subject to a training program for new employees or refresher training (if appropriate) | ||
* To check for risks of disclosing confidential or otherwise sensitive or proprietary information (e.g. in the context of existing or emerging intellectual property) | * To check for risks of disclosing confidential or otherwise sensitive or proprietary information (e.g. in the context of existing or emerging intellectual property) | ||
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== C. Resources == | == C. Resources == | ||
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Online registry platforms: | Online registry platforms: | ||
* Animal Study registries | * Animal Study registries | ||
Revision as of 17:17, 5 September 2020
A. Background & Definitions
Preregistration refers to a process of registration of study plan and data analysis plan before conducting a study.
Registered Report is a maximal form of registration, in which study manuscript that includes the study hypothesis, rationale, methods, experimental plan and a detailed analysis plan is peer reviewed (Stage 1) before study data is collected. After data collection, the final manuscript that includes results and discussion sections undergoes a conventional peer review (Stage 2) where adherence to the original (Stage 1) procedures is confirmed. Following favorable reviews and, regardless of study results, the manuscript is accepted for publication (Munafo et al. 2017, BMJ Open Science, Registered Reports Guidelines).
Benefits of preregistration * Increases transparency
- Serves to reduce:
- The risk of publication bias
- "HARKing" (hypothesizing after the results are known)
- P-hacking (analytical decisions after the results are known)
- In case of a Registered Report, registration helps also against "CARKing" (unjustified critique of the article by reviewers after the results are known; Munafo et al. 2017).
B. Guidance & Expectations
- If study is done to inform a knowledge claim (2.1.4 Purpose of research), it is strongly recommended to preregister the study protocol before data are collected.
- It is strongly recommended to register systematic review protocols.
- Training on planning and benefits of preregistration is highly recommended.
PLEASE DO NOT FORGET
- To consider adding this subject to a training program for new employees or refresher training (if appropriate)
- To check for risks of disclosing confidential or otherwise sensitive or proprietary information (e.g. in the context of existing or emerging intellectual property)
C. Resources
Online registry platforms:
- Animal Study registries
- Center for Open Science - [https://cos.io/prereg/]
- AsPredicted - [3]
- PROSPERO, a platform for registering a systematic review of animal studies - [4]
- OSF for Registered Reports - [5]
Publications:
- Nosek BA, Ebersole CR, DeHaven AC et al. (2018) The preregistration revolution. Proc Natl Acad Sci U S A. 115:2600-2606. PubMed [6]
- De Vries RBM, Hooijmans CR, Langendam MW, et al. (2015) A protocol format for the preparation, registration and publication of systematic reviews of animal intervention studies. Evid Based Preclin Med. 2:1–9. [7]
- Chambers C (2014) Registered Reports: A change in scientific publishing
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